Keep an eye on for signs of urinary retention or diminished gastric motility if oliceridine is coadministered with anticholinergics.enasidenib will improve the level or outcome of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Observe. Enasidenib (a weak CYP2C19 inhibitor) may enhance systemic exposure of sensitive CYP2C19 sub